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Publication Permission Requests
Example Input Mode:
Partner Data
CBIS
Matrix
Example Data Type:
Secondary Screen (Kd)
Primary Screen(% control or competition)
If the input file contains Primary and Secondary Data, use:
Primary
Secondary
Assay Data File:
.txt or .csv format - download examples:
Bromodomain
Kd
Primary
To highlight spots, select a compound(s), click 'fill' and select entries.
Create Images for:
VX-745
Highlight These Spots (
fill
):
VX-745|ABL2|1900
VX-745|BLK|3100
VX-745|CSF1R|2600
VX-745|DDR1|1100
VX-745|EPHA1|4700
VX-745|EPHB1|6200
VX-745|FGR|1300
VX-745|FYN|2100
VX-745|LCK|4600
VX-745|LYN|1700
VX-745|p38-alpha|2.8
VX-745|p38-beta|74
VX-745|PDGFRA|8800
VX-745|PDGFRB|8400
VX-745|SRC|5500
VX-745|YES|1600
VX-745|ABL2
VX-745|BLK
VX-745|CSF1R
VX-745|DDR1
VX-745|EPHA1
VX-745|EPHB1
VX-745|FGR
VX-745|FYN
VX-745|LCK
VX-745|LYN
VX-745|p38-alpha
VX-745|p38-beta
VX-745|PDGFRA
VX-745|PDGFRB
VX-745|SRC
VX-745|YES
VX-745|ABL2|1900
VX-745|BLK|3100
VX-745|CSF1R|2600
VX-745|DDR1|1100
VX-745|EPHA1|4700
VX-745|EPHB1|6200
VX-745|FGR|1300
VX-745|FYN|2100
VX-745|LCK|4600
VX-745|LYN|1700
VX-745|p38-alpha|2.8
VX-745|p38-beta|74
VX-745|PDGFRA|8800
VX-745|PDGFRB|8400
VX-745|SRC|5500
VX-745|YES|1600
clear
Select Highlight spots color from Pallette:
(also used in table view)
Tree Image Options
Restore default options
Spot options:
IndianRed
PaleGreen
Gold
PowderBlue
Fill?
Outline?
Outline thickness:
1
2
3
4
5
Select Spots Color from Pallette:
(spot highlight color below)
micro
nano
Spot Size:
Scaling Factor:
.1
.2
.3
.4
.5
.6
.7
.8
.9
1
1.1
1.2
1.3
Area increase factor:
100%
90%
80%
70%
60%
50%
(per change of 10x Kd or 10% Competition)
Legend options:
Left align Text
Right align Text
Label options:
Compound Name?
Compound Name Font:
.5
1
1.5
2
Show Assay Panel information?
Show Panel Spots?
Append Concentration? (i.e., 'AB500@1000nm'; check before loading.)
Background Image:
Target labels?
Dark Tree Branch image?
Hide Lipid, Mutant, ATypical and Pathogen?
Spot options:
Spot Color transparency level:
none
low
medium-low
medium
high
no color
Spot Cutoff Value:
Kd (nM) (Blank for no cutoff)
Spot outline only?
Format:
JPEG(200KB per image)
Publication Quality(5MB image)
Create Publication Quality (5MB bitmap) Image for:
Select Compound
VX-745
size/quality
100
90
80
70
60
50
40
30
% of original
White Space Border:
Yes
No
Preview and Highlighting
Highlight an assay by clicking on the spot or checking the box next to the Gene Symbol Name.
Click 'Update' to create the new images.
Compound To Highlight:
None
VX-745
Highlight Panel?
* WildType kinase assays appear in both the main TREEspot and Mutant kinase dendrogams.
Human Kinome image created by KINOMEscan.
2 images created. To download (copy and paste) all images to your local machine click Open/Browse Image Folder.
Images Saved To:
D:\Eurofins\PROD\Applications\FrontOffice_Discovery\StudyManagement\TreeSpot\HTSTools\TreeImages\827_j1hg2q4hjeyky3bt5k4qvdxm\
Open/Browse Image Folder
View Options:
(These options do not modify the images that have been created, only the view on this page)
VX-745
Legend
Show Selected
Size:
Select Size
small
medium
full size
Images per Row:
1
Legend Resize?
Hover the cursor to identify spots and click to highlighted it. To save an image click the Zoom/Download link.
Zoom/Download
Highlight
Locate an Assay
ABL2
CSF1R
DDR1
FGR
FYN
LYN
p38-alpha
p38-beta
YES
Legend
Data Table View:
Show All Data
Only Selected Compounds/Trees
TREE
spot
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